If you thought 23andMe testing was just for learning about your ancestry we've
got a lot to share today and to help us dig into this is Alyson Roux.
Alyson, do you want to tell us a little bit about what your specialty is here?
Sure, I am a clinical nutritionist. I'm a CNS and I work with people who are struggling with
their relationship to food and I use a variety of tools including nutritional
genomics where sometimes we take a look at their DNA and how we might just make
the way that their metabolizing food a little bit more efficient so I have
interpreted both of your 23andMe raw files using a couple of different
programs and we're gonna talk through a few micronutrient implications that may
be beneficial for preventative health or if you have any kind of health conditions going on.
Okay, and for those people who might be a little confused...
This isn't like you do your 23andMe tests and you get it back and it tells
you all this. This is we got our results back we downloaded the raw data which is
an option that you can do and then we sent it to Alyson and then you go through and decipher.
Exactly here's the other cool part is that genetics we used to
think in the 90s when we started doing the human genome project was that
we thought that genetics were destiny, we thought okay here's your code like a
computer it's what it is – but that's not actually the case and genetics and some
of these common mutations think of them more like light switches where as you go
through life the light switches get turned on or turned off so perhaps you
have a year where you're working really hard
you're not perhaps eating enough of a varied diet you try maybe a crash diet
and it's really limited and you missed out on some nutrients maybe you get
fired from a job it's a tough year and that might turn some of those light
switches on that stress might turn on some of these mutations perhaps you have
some time where you simply have had very low stress
you're cooking like a champion or you have a private chef or you just
found like a really good meal delivery service or whatever works for your lifestyle
and perhaps through that and gentle like joyful exercise you're in
good shape and those light switches get turned off so the purpose of figuring
out what these mutations are it's just to simply try to turn off all those
light switches and and allow you to live kind of a more optimal life.
Yeah or like if our body was an iPhone and our enzymes are like the apps you're saying
that these can be like the updates to the apps.
Exactly!
I'm nailing this!
That's amazing.
Okay, so let's start with our editorial warrior
and so we're gonna go through just a few key what I call micronutrient
SNPs so a SNP is it's basically just a single little mutation it's one little
SNP in the code that it's going to change how your body metabolizes a
certain nutrient potentially... if it's triggered. So you had a couple of
superoxide dismutase SNPs and there's a lot of these there isn't just one of any
of these was a lot of them that come together to code for these these enzymes
so when somebody has this kind of result I just tend to recommend increasing
antioxidant rich foods so bright colored vegetables and fruits awesome so here's
the area that I think is probably the most popular to talk about in
nutritional genomics...
Is it about weight gain?
No!
What is it!?
It's about folate! Folate, also known as vitamin B9, and commercially known as
folic acid – folate is found in foods like dark leafy greens, broccoli, liver which
most people don't like but I grew up eating liver and I think it's delicious
I've been meaning to incorporate liver in!
Folate helps us make red blood cells it helps us actually even with some
making of DNA and it's something that generally when we have enough of it in
our diet we have reduced risk of colon cancer and reduced cardiovascular risk
so we want to make sure that we have adequate levels of folate
so then as far as supplements that we have here which ones are there any that
you would recommend for Zena to take?
So I think vitamin D would probably be a
good idea and then the other one some kind of B12, especially if you're
feeling low energy because of those SNPs might be helpful I tend to like to
make sure you have B12 as well as the B6 and B9 which is folate
Okay should we move on to you?
Super RD!
So one thing I wanted to point out for you that I find really interesting
there's this enzyme that
helps us convert Vitamin A that's from plants into Vitamin A that we can use
and do stuff with and when we eat Vitamin A in plants which is usually in
beta carotene form there's that just extra step couple steps that we have to
then convert it so we can help make collagen and support our skin and all of
those kinds of things and fight off oxidants so you have basically none of
the mutations in that enzyme so that's actually fairly rare and usually people
who don't have any of those mutations can get away with being a vegetarian
Oh, interesting...
So in terms of your sulfation SNPs they're in really good
shape so if you're having hormone balance issues it would potentially the
likelihood of it being related to that is low.
Okay. No, I think my hormones are okay.
My period comes like clockwork.
That's great.
And then I wanted to show you your Vitamin D
receptor gene so there's no mutation there it's totally wild type
which about 40 percent of the population has that is wild-type there so there you
have less of the risk of having a Vitamin D deficiency but that still
means you need to get it checked because it's so important with that I just covered those
basic kind of micronutrients so just a couple vitamins, the vitamin A, the Vitamin D...
the folate, B12 and then some of the minerals with magnesium and our amino
acids that we talked about it's like how to activate methionine into SAM-e so we
can metabolize our neurotransmitters efficiently
So what supplements would you recommend for Sarah then?
So for Sarah if your Vitamin D status is
healthy and and adequate you probably don't need to be taking any Vitamin D
also because you don't have the mutation
And then what about the... maybe the
Vitamin C also in this one for the antioxidant I think that's what it is
that's actually the the most important thing probably for you is to focus on
antioxidants and the cofactors that help in liver detoxification
Okay, cool
Amazing!
Well I think this is so cool I know when I got my 23andMe results you
know there's the health report in the system and mine just kind of said like
there were like two genes that were identified as off
maybe celiac and macular eye degeneration were the two that flagged so I
think this is such a cool resource I'm so appreciative that we got to do this
with you today I'm curious if other people are interested in this
how should they seek out this service?
So if other people are interested in this you
can upload your own 23andMe raw file to Genetic Genie
That's the nice free option
That's the free option or you can find a practitioner who uses some kind of other program
like the Methylgenetic Nutrition Analysis from DNASupplementation.com
or there's a variety of other tools
I think it's always better to work with a clinician who actually knows – who's
familiar with nutritional genomics it is a very new science and the literature is
is – it exists we know that we have some evidence for this but it's still
limited and new so it's really important to interpret with that caveat but it can
be a game-changer if you're really struggling with just that final piece to
optimizing how you feel
And where can people find you if they want to work
with you?
Oh! You can come to my website I'm at AlysonRoux.com
And we'll link it below too so if you want to talk to Alison and have her
help you interpret your results or dig into what's going on nutritionally she
can absolutely do that she's a great resource
Thanks so much for watching, guys.
If you like this video give it a thumbs up and comment below with
anything else you want to see. Bye!
you
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